Precision Diagnostics for Definitive Clinical DecisionsBreast carcinoma
ERPRHER2Ki-67GATA3
Support receptor status, proliferation assessment and breast lineage where indicated.
Request / discuss in PATHOSURE® App →Home → IHC → Disease-Based Panels
Immunohistochemistry
Precision on Every Slide.
Disease-based IHC panels organized around clinical questions, tumour lineage and differential diagnosis.
Disease-based portfolio
Choose the diagnostic question first.
Panel selection is guided by morphology and clinical context. Final interpretation belongs to the qualified reporting pathologist.
Continue in the PATHOSURE® AppSubmit referrals, request tests, track cases and access available reports through the connected digital workflow.
Open App →Lung carcinoma
TTF-1p40Napsin ACK7
Support adenocarcinoma vs squamous differentiation and pulmonary lineage in context.
Request / discuss in PATHOSURE® App →Colorectal / GI adenocarcinoma
CDX2CK20CK7
Support intestinal differentiation and metastatic adenocarcinoma work-up.
Request / discuss in PATHOSURE® App →GIST / mesenchymal GI tumour
S100SOX10Vimentin
Support differential evaluation of a suspected mesenchymal/neural-pattern GI tumour. Definitive GIST work-up may require additional GIST-specific markers.
Request / discuss in PATHOSURE® App →Prostate carcinoma
PSANKX3.1
Support prostatic lineage in an appropriate morphological context.
Request / discuss in PATHOSURE® App →Renal tumour
PAX8RCCCAIX
Support renal/Müllerian/thyroid lineage questions and renal tumour differential diagnosis in context.
Request / discuss in PATHOSURE® App →Thyroid tumour
TTF-1PAX8Thyroglobulin
Support thyroid lineage and differential diagnosis in context.
Request / discuss in PATHOSURE® App →Müllerian / gynecologic tumour
PAX8WT1CK7ERPR
Support Müllerian lineage and selected gynecologic tumour differentials.
Request / discuss in PATHOSURE® App →Urothelial carcinoma
GATA3p40p63CK7CK20
Support urothelial and squamous differentiation in context.
Request / discuss in PATHOSURE® App →Melanocytic tumour
S100SOX10
Support melanocytic/neural-crest differentiation.
Request / discuss in PATHOSURE® App →Neuroendocrine tumour
SynaptophysinChromograninCD56
Support neuroendocrine differentiation in an appropriate morphological context.
Request / discuss in PATHOSURE® App →Lymphoma / lymphoid work-up
CD45CD20CD3CD30CD15BCL2BCL6CD10MUM1Cyclin D1
Lineage and phenotype support for selected lymphoid differentials; panel selection should be pathologist-directed.
Request / discuss in PATHOSURE® App →Metastatic / unknown primary
AE1/AE3CK7CK20TTF-1CDX2PAX8GATA3
Broad epithelial and lineage-oriented work-up of selected metastatic carcinomas.
Request / discuss in PATHOSURE® App →Squamous carcinoma
AE1/AE3p40p63
Support squamous differentiation in the appropriate morphological setting.
Request / discuss in PATHOSURE® App →Mesenchymal phenotype support
VimentinS100SOX10
Limited supportive assessment in selected mesenchymal/neural-pattern differentials; not a standalone sarcoma classification panel.
Request / discuss in PATHOSURE® App →GIST example
GIST is included in the disease-panel catalogue.
The website presents GIST as a dedicated diagnostic panel. The current portfolio includes supportive markers such as S100, SOX10 and Vimentin; classic GIST-specific markers such as CD117/KIT and DOG1 should only be displayed as available once added and validated in the operational portfolio.
IHC workflow
Morphology → diagnostic question → marker/panel selection → controls/QC → staining → review → integrated interpretation.
IHC Referral Requirements →Clinical note: IHC is an ancillary diagnostic tool. No panel should be interpreted in isolation, and a listed marker does not by itself establish a diagnosis.
Experienced Pathologists
Specialist interpretation and reporting are supported by experienced pathologists within the PATHOSURE® diagnostic workflow.